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의학 논문

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화병환자의 불면증 침치료가 인체의 자율신경계에 미치는 영향
초록 Objectives: The purpose of this research is to examine effects of acupuncture treatment on the auto-nomicnervous systems of Hwa-byung patients with insomnia. Methods: The study was performed througha patient-assessor blind, randomized, placebo-controlled trial in which the volunteers, data collectors,and analysts were unaware of which individuals were re-ceiving the treatment. A total of thirty-sevenvolunteers were divided into 2 groups. Eighteen subjects were placed into a trial group and 19 subjectsinto a control group using a randomization table. The trial group was treated with bilateral Shigu, Ahnmyun,B62 (Shinmaek), and K6 (Chohae), while the control group was not given any other treatment.The ISI (Insomnia Severity Scale) was measured as the first evaluative instrument, and then a comparativeanalysis was conducted by comparing the re-sults with those measured by ANS (BVP/HR, respiration rate,peripheral temperature, skin con-ductance, EMG).Results: In the BVP/HR, statistically significant decreases werefound in those from the trial group compared to those of the control group. Skin conductance was found to besignificantly increased in the trial group, as compared to the control group. However, there were no significantdifferences be-tween the groups with respect to peripheral temperature, respiration rate, and EMG.Conclusions:The results suggest that acupuncture treatment is effective in the treatment of hwa-by-ung patients...
한음 ㆍ 2024.03.22 ㆍ 추천 0 ㆍ 조회 798
마음챙김 명상과 이정변기요법을 이용한 공황장애 그룹치료 효과에 대한 임상적 고찰
초록 Objectives: This study was conducted to evaluate the clinical effects of group therapy for Panic disorderpatients based on Mindfulness & Li-Gyeung-Byun-Qi therapy. Methods: The FFMQ, BDI, STAI, STAXI,Panic attack, Anticipatory anxiety and subjective improvement of three Panic disorder patients werecompared pre- and post-treatment when given Mindfulness & Li-Gyeung-Byun-Qi therapy. Results: 1) Afterthe patient in case 1 underwent 5 weeks of group therapy for Panic disorder, the Mindfulness meditationscore was slightly improved, anxiety and depression were significantly decreased, and expression of angerwas also improved. In addition, the Panic attack and Anticipatory anxiety became more stable in the objectiveevaluation, while 'Extreme improvement' was shown in the subjective evaluation.[원문 보기 클릭]
한음 ㆍ 2024.03.22 ㆍ 추천 0 ㆍ 조회 824
암환자 22예에 대한 한방병원 내원동기 및 한방치료 만족도 조사
초록 Objectives: This study aimed to understand the motives for visiting oriental medical hospital and thesatisfaction degree of cancer patients, in order to increase the satisfaction rate of oriental medicineamong cancer patients. Methods: The data were collected from inpatients who responded to a self-reportquestionnaire. Independent t-test, analysis of variance (ANOVA), and correlation analysis were used fordata analysis. Results: The most prominent motive for visiting oriental medical hospital was recurrenceprevention and energy recovery. In oriental medical care, positive responses appeared in the order of 'Acupuncture','Pharmacopuncture', 'Enzyme therapy', 'Foot bath therapy', and 'Moxibustion'. According to the research on medicalsatisfaction degree, the overall satisfaction degree was 4.56. On each field, satisfaction degree related to the doctorservice was 4.64, and satisfaction degree of using the procedure was 4.47. Conclusions: Cancer patients mostly visitedoriental medical hospital for recurrence prevention and regaining energy, and the service distribution of oriental medicalhospital was almost equal without being concentrated on the specified social classes.[원문 보기 클릭]
한음 ㆍ 2024.03.22 ㆍ 추천 0 ㆍ 조회 802
한의학 칠정(七情)에 기반을 둔 핵심감정평가척도를 이용한 공황장애 환자의 특성 연구
초록 Objectives: The purpose was to conduct a characteristic study on panic disorder patients through TheCore Emotional Assessmental Questionnaire (CEAQ), followed by a correlation analysis with STAI, STAXIand BDI.Methods: We analyzed medical records of 62 patients who had visited ○○ University hospital,ori-ental neuropsychiatric department and completed the The Core Emotional AssessmentalQuestionnaire (CEAQ), STAI, STAXI, and BDI. Finally, 20 patients who were diagnosed as Panic Disorderaccording to DSM-Ⅴ (2013) were included in the study. Patient data was analyzed by Chi-Square test,frequency analysis, independent t-test, one-sample t-test, and correlation analysis using the SPSS(Statistical Package for the Social S 21.0 Version).Results: 1. Panic disorder patients experienced lessHui, and more Sa (思), Gong (恐), Kyeong (驚), and Bi (悲). 2. Female Panic disorder patientsexperienced more Hui (喜), as compared to male patients; whereas, male patients experienced more No(怒). 3. U (憂), Bi (悲), Sa (思), Gong (恐), and Kyeong (驚) emotions of Panic disorder patients werecorrelated to STAI-S, STAI-T, and BDI.[원문 보기 클릭]
한음 ㆍ 2024.03.22 ㆍ 추천 0 ㆍ 조회 818
암 환자의 핵심칠정척도를 활용한 정서적 특성 연구
초록Objectives The Purpose of this study was to conduct a characteristic study on cancer patients using theCore Seven Emotions Inventory (CSEI) followed by a correlation analysis with STAI, STAXI andBDI.Methods This study was conducted by analyzing the medical records of 21 patients who had visited○○ University Oriental hospital and completed the Core Seven Emotions Inventory (CSEI), BAI, and BDI.A total of 21 patients diagnosed with Cancer were analyzed using SPSS (Statistical Package for theSocial Science, IBM, United States of America, Version 22.0). Frequency Analysis, independent t-test,one-sample t-test, and correlation analysis were conducted.Results 1. The Seven EmotionCharacteristics of the Cancer patients showed a fairly stable emotional Distribution. The Gong (恐) andKyeong (驚) emotions were relatively higher than U (憂), Bi (悲), Sa (思), Hui (喜), No (怒). 2. Accordingto Gender, Female patients exhibited higher Sa (思) and Kyeong (驚) emotions while male patientsexhibited higher Bi (悲) Emotion. 3. No (怒), U (憂), Bi (悲), Sa (思), Gong (恐), and Kyeong (驚)emotions showed a high correlation with the BDI and BAI scores of cancer patients.[원문 보기 클릭]
한음 ㆍ 2024.03.22 ㆍ 추천 0 ㆍ 조회 822
비알코올성 지방간 세포 모델에서 소분청음의 지방증 완화 효능 연구
초록 Objectives : The purpose of this study is to evaluate the anti-lipogenic effect of Sobuncheong-eum on non-alcoholic fatty liver disease in free fatty acid induced cellular model. Methods : HepG2 cells were treated with palmitate for 24h to overload intracellular triglyceride (TG) content in the presence or absence of Sobuncheong-eum extract.After palmitate treatment, Intracellular TG content was measured with TG assay kit. Several lipogenesis related markers, including AMP-activated protein kinase (AMPK),sterol regulatory element-binding transcription factor-1c (SREBP-1c), acetyl-CoA carboxylase (ACC), and fatty acid synthase (FAS), were assessed using Western-blot analyses and RT-PCR. Results : Palmitate markedly increased intracellular TG in HepG2 cells, and which were alleviated by coadministered Sobuncheong-eum extract.Sobuncheong-eum extract activated AMPK, which plays a key role in reducing hepatic lipid accumulation, and reduced lipogenic fators, SREBP-1c, ACC, and FAS. Conclusions : Taken together, it is conceivable that Sobuncheong-eum has an potential to alleviate steatosis, and which may be mediated by activating AMPK at least in part.[원문 보기]
한음 ㆍ 2024.03.22 ㆍ 추천 0 ㆍ 조회 816
DITI를 활용한 청소년기 특발성 척추측만증에 대한 임상적 고찰
초록 Objectives : This study was performed to investigate the correlation between Cobb's angle and digital infrared thermographic imaging(DITI) on adolescent idiopathic scoliosis. Methods : A total of 56 patients with adolescent idiopathic scoliosis were classified into four groups according to their Cobb's angle.Four groups were made for each increment of $5^{circ}$: group $5-10^{circ}$, group $11-15^{circ}$, group $16-20^{circ}$, and group $21-25^{circ}$.Next we checked thermal differences of 6 acupoints(GB21, BL13, BL15, BL20, BL23, BL26) on DITI and analyzed correlation by SPSS ver. 20.0.0 for windows. Results :1. The average patient age was approximately 13 years old.2. The majority of patients complained of pain on both sides.3. Significant correlation was found between group $11-15^{circ}$ and group $16-20^{circ}$, group $16-20^{circ}$ and group $21-25^{circ}$ on Simsu(BL15) by Duncan test. Conclusion : Using DITI, Simsu(BL15) is expected to be a valid indicator for the diagnosis and treatment of adolescent idiopathic scoliosis.[원문 보기]
한음 ㆍ 2024.03.22 ㆍ 추천 0 ㆍ 조회 832
천마의 용량에 따른 기억력 향상 효과에 대한 연구
초록 Objectives: This study was designed to investigate the dose-dependent effects of Gastrodia elata Blume for memory improvement. Methods: This study was a 12-weeks, double blind, and comparative clinical study.Those who were eli-gible worked with a group of healthy seniors, all 60 years of age or older.22 subjects were randomized either to Gastrodia elata Blume powder form that was steeped in hot water or placebo.We measured the faculty of memory by using MMSE-K, Digit Span, Letter Fluency Test, Word List Memory Test, and Trail Making Test, and again after 12 weeks. Results:1) Neither Gastrodia elata Blume groups nor control have a difference in MMSE-K, Digit Span, Letter Fluency Test, and Trail Making Test.2) Gastrodia elata Blume group showed significant advances in immediate recall 1 and 2 of Word List Memory Test, and 3 g group show better results than the 4 g group.3) 4 g Gastrodia elata Blume group showed significant advances in the recognition of Word List Memory Test. Conclusions: The results suggest that positive effects on memory improvement due to Gastrodia elata Blume depend on the amount.[원문 보기]                  
한음 ㆍ 2024.03.22 ㆍ 추천 0 ㆍ 조회 853
반하후박탕(半夏厚朴湯)의 사회·심리적 스트레스에 대한 실험적 연구(實驗的 硏究)
초록 Objectives: This study is designed to investigate the effects of Banhahubak-Tang Extract (BHTe) on stress. Methos: BHTe was fed to ICR male mice ($20{pm}2g$) orally with the dose of 100 mg/kg/day for five days.Mice were then exposed to sociopsychological stress by observing foot shock stressed mice for one hour for five days while restrained. Results:1) The BHTe-administered group showed a tendency of decreasing of serum corticosterone secretion compared with the control group.2) The BHTe-administered group showed an increase in noradrenalin secretions in the dorsal cortex of the brain, but it was not significant.3) BHTe administration had no effect on the brain level of lipid peroxidation.4) BHTe administration decreased the serum level of lipid peroxidation.5) BHTe administration decreased the Cu,Zn-SOD in the brain.6) BHTe administration had no effect on catalase activity in the brain.7) BHTe administration had no effect on the brain level of GSH.8) BHTe administration increased the serum level of DPPH free radical scavenging activity, but not significantly enough to make a comparison with BHT.9) The elevated plus-maze test is designed to detect the effect of anxiolytic drugs.The BHTe group showed a significant increase in latency time. Conclusions: These results suggest that BHTe can effectively rid the subject...
한음 ㆍ 2024.03.22 ㆍ 추천 0 ㆍ 조회 829
반하(半夏)가 스트레스로 인한 생쥐의 뇌조직 유전자변화에 미치는 영향 연구
초록 Objectives: Pinelliae Rhizoma has traditionally been used as an anti-depressant in oriental medicine.This study is to investigate the effect of Pinelliae Rhizoma extract (PRe) on psychological stress in genome wild expression of mice. Methods: After giving physical stress to mice, PRe was orally administered with 100 mg/kg/day for five days.After extracting whole brain tissue from the mice, their genome changes were observed by micorarray analysis method.The genome changes were analyzed by IMAGENE 4.0, TREEVIEW, FatiGo algorithems, BOND database, cytoscape program, etc. Results:1. PRe administered group were remained at normal level; 60% of increase was shown in expressed genes by physical stress, and 65% of decrease was shown in expressed genes by psychological stress.2. Genes with increased expression in control group that remained at a normal state in PRe administered group were involved with the gene of a cellular metabolic process on biological process, protein binding on molecular function, and cell part on cell composition. The pathway was found to be cytokin-cytokin receptor interaction.3. Genes with decreased expression in control group that remained at a normal state in PRe administered group were involved with the gene of a cellular metabolic process on biologiacl detail and coupled ATPaes activity on molecular...
한음 ㆍ 2024.03.22 ㆍ 추천 0 ㆍ 조회 820
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